脱铁转铁蛋白 人
转铁蛋白(Transferrin)
CAS: 11096-37-0
化学式: C16H22N6O4
| 中文名 | 转铁蛋白 |
| 英文名 | Transferrin |
| 别名 | 转铁蛋白 人转铁蛋白 铁传递蛋白 全-转铁蛋白 大鼠转铁蛋白 脱铁转铁蛋白 人 铁传递蛋白(人) TRANSFERRIN 人 HOLO-TRANSFERRIN 人 |
| 英文别名 | Transferrin apo-transferrin holo-transferrin HUMAN TRASFERRIN HOLO-TRANSFERRIN HUMAN TRANSFERRIN HUMAN APO-TRANSFERRIN HUMAN SEROTRANSFERRIN apo-transferrin mouse HOLO-TRANSFERRIN HUMAN HUMAN HOLO-TRANSFERRIN apo-transferrin bovine holo-Transferrin bovine HOLO-TRANSFERRIN BOVINE apo-transferrin guinea pig transferrin from bovine serum Transferrin, Apo-, Human Plasma Transferrin, Holo, Human Plasma Transferrin, Holo, Bovine Plasma Transferrin, Apo-, Bovine Plasma apo-transferrin human cell culture*tested transferrin bovine holo-form*iron-saturated cell Transferrin, Apo-, Tissue Culture Grade, Human Plasma Transferrin, Holo, TC Grade, Pyrogen-Free, Human Plasma Transferrin, Apo-, TC Grade, Pyrogen-Free, Human Plasma |
| CAS | 11096-37-0 |
| EINECS | 234-318-8 |
| 化学式 | C16H22N6O4 |
| 分子量 | 362.38368 |
| 水溶性 | Soluble in water (50 mg/ml). |
| 溶解度 | H2O: 50 mg/mL |
| 存储条件 | 2-8°C |
| 外观 | 粉末 |
| MDL号 | MFCD00131337 |
| 危险品标志 | Xi - 刺激性物品 |
| 风险术语 | 36/37/38 - 刺激眼睛、呼吸系统和皮肤。 |
| 安全术语 | S26 - 不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。 S37/39 - 戴适当的手套和护目镜或面具。 |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 21 |
| TSCA | Yes |
| 参考资料 展开查看 | 1. 吕娟 周刚 李振莲 杜艳 朱叶青.凝胶过滤色谱法测定蛋白胨中多肽的相对分子质量分布[J].食品安全质量检测学报 2020 11(15):5131-5136. 2. 杨凯,李一鹏,刘英富,程远驰,汤锋武,梁冰,徐忠伟,陈旭义.大鼠皮质少突胶质细胞培养条件的优化[J].中国组织工程研究,2016,20(29):4328-4333. 3. 江力, 谈弋, 王军. 转铁蛋白修饰的甲基莲心碱纳米脂质体的研制及脑靶向性考察[J]. 中国药师, 2019, 22(03):447-450. 4. 罗明志, 余培丽, 金阳,等. 血根碱对大鼠气道平滑肌细胞生物力学特性的影响[J]. 生物医学工程学杂志, 2018, v.35(04):89-97. 5. 肖语涵,胡月,黄沛力.荧光光谱与等温滴定量热法研究碲化镉量子点与转铁蛋白的相互作用[J].毒理学杂志,2020,34(06):449-453. 6. 杨卓一,陈会,白思益,帕梅拉·帕尔哈提,侯敬丽,袁运生.伴刀豆球蛋白A诱导肝细胞损伤的磷酸化蛋白质组学研究[J].上海交通大学学报(医学版),2021,41(01):1-7. 7. 吕娟,周刚,李振莲,杜艳,朱叶青.凝胶过滤色谱法测定蛋白胨中多肽的相对分子质量分布[J].食品安全质量检测学报,2020,11(15):5131-5136. 8. Zhu, Chunling, et al. "Construction of synergistic therapy system with multiple therapeutic effects based on CuS@ Tf nanodots." Journal of Inorganic Biochemistry 209 (2020): 111100.https://doi.org/10.1016/j.jinorgbio.2020.111100 9. Guichun Mo, Xinxin He, Chunqin Zhou, Dongmei Ya, Jinsu Feng, Chunhe Yu, Biyang Deng,A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha- 10. Zhang, Aitang, et al. "A Target‐Directed Chemo‐Photothermal System Based on Transferrin and Copolymer‐Modified MoS2 Nanoplates with pH‐Activated Drug Release." Chemistry–A European Journal 23.47 (2017): 11346-11356.https://doi.org/10.1002/chem.201701916 11. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 12. Aitang Zhang, Aihua Li, Wei Zhao, Guowen Yan, Bingping Liu, Mengli Liu, Meixiu Li, Bingbing Huo, Jingquan Liu,An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually control 13. [IF=13.273] Aitang Zhang et al."An efficient and self-guided chemo-photothermal drug loading system based on copolymer and transferrin decorated MoS2 nanodots for dually controlled drug release."Chem Eng J. 2018 Jun;342:120 14. [IF=9.518] Guichun Mo et al."A novel ECL sensor based on a boronate affinity molecular imprinting technique and functionalized SiO2@CQDs/AuNPs/MPBA nanocomposites for sensitive determination of alpha-fetoprotein."Biosens Bioelectron. 2019 Feb;126:558 15. [IF=6.331] Wei Zhao et al."Transferrin-decorated, MoS2-capped hollow mesoporous silica nanospheres as a self-guided chemo–photothermal nanoplatform for controlled drug release and thermotherapy."J Mater Chem B. 2017 Sep;5(35):7403-7414 16. [IF=10.618] Cai-Feng Shi et al."Ultrasensitive plasmon enhanced Raman scattering detection of nucleolin using nanochannels of 3D hybrid plasmonic metamaterial."Biosens Bioelectron. 2021 Apr;178:113040 17. [IF=7.1] Rui Duan et al."Integrating boronate affinity controllable-oriented surface imprinting nylon wire and pH-triggered allochroic-graphene oxide for ultrasensitive detection of glycoprotein."Sensor Actuat B-Chem. 2021 Mar;330:129310 18. [IF=5.875] Yanyan Yin et al."Cascade catalytic nanoplatform based on ions interference strategy for calcium overload therapy and ferroptosis."Int J Pharmaceut. 2021 Sep;606:120937 19. [IF=4.155] Chunling Zhu et al."Construction of synergistic therapy system with multiple therapeutic effects based on CuS@Tf nanodots."J Inorg Biochem. 2020 Aug;209:111100 20. [IF=2.649] Xingzhen Zhang et al."Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma."Med Sci Monitor. 2019; 25: 9737–9751 21. [IF=9.229] Miaomiao Han et al."Amyloid Protein-Biofunctionalized Polydopamine Nanoparticles Demonstrate Minimal Plasma Protein Fouling and Efficient Photothermal Therapy."Acs Appl Mater Inter. 2022;XXXX(XXX):XXX-XXX 22. [IF=6.057] Zhi-Heng Pan et al."Poly(caffeic acid)-coated molecularly imprinted magnetic nanoparticles for specific and ultrasensitive detection of glycoprotein."Talanta. 2022 May;241:123240 转铁蛋白冻干粉需要保存在冷藏状态下，使用之前再溶解。一般用 PBS 或者其它合适的溶剂在室温下将转铁蛋白冻干粉溶解成储液，浓度在 0.5-2.0mg/ml,然后用无菌滤膜进行过滤，滤液可在无菌条件下 2-8℃保存 30 天。 |
脱铁转铁蛋白 人 - 介绍
转铁蛋白是血浆中主要的铁传递蛋白，为细胞分化和细胞代谢提供所需的铁。研究发现所有的细胞生长都离不开转铁蛋白。不但维持正常的细胞代谢依赖于以生物活性形态存在的铁，铁还是一些酶的辅助因子，比如 RNA 聚合酶，DNA 合成酶。同时也是血红蛋白的重要组成部分。
最后更新：2022-10-16 17:12:02
脱铁转铁蛋白 人 - 使用说明
转铁蛋白对于绝大部分细胞系在无血清培养基中生长是必需的，研究表明饱和铁形态的转铁蛋白对于促进细胞生长是最有效的形态。对于杂交瘤，黏连细胞和悬浮细胞系，在细胞培养过程中，应保持培养基中转铁蛋白浓度在 0.5-100μ g/ml。针对不同的细胞系，需要选择最合适的浓度。
最后更新：2023-08-16 21:32:38
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